PRIMAL AR

Essentials for Seasonal Allergy Relief

Seasonal allergies, often triggered by pollen, mold, and other environmental allergens, can significantly impact quality of life, leading to symptoms such as sneezing, itchy eyes, runny nose, and nasal congestion. E=ective management of these symptoms is crucial for maintaining daily function and overall well-being. In this post we explore the role of Primal AR and it’s five key ingredients—Quercetin, Stinging Nettle Leaf, Bromelain, N-Acetylcysteine (NAC), and Vitamin C— and their role in alleviating seasonal allergy symptoms.

Primal AR Ready4 Support

Primal AR is a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for seasonal challenges caused by common environmental allergens. This powerful combination actively promotes healthy nasal and sinus passages for individuals with elevated histamine and respiratory irritation.

Quercetin

Quercetin is a flavonoid found in various fruits, vegetables, and grains. It is known for its antiinflammatory and antioxidant properties.

• Mechanism of Action: Quercetin stabilizes mast cells, which are responsible for releasing histamines that cause allergic reactions. By preventing mast cell degranulation, quercetin helps to reduce the intensity of allergic responses.
• Clinical Evidence: Studies have shown that quercetin supplementation can decrease the severity of allergy symptoms. Research published in Current Drug Targets suggests that quercetin's ability to inhibit histamine release makes it a beneficial supplement for managing allergy symptoms.

Stinging Nettle Leaf

Stinging nettle (Urtica dioica) is a plant traditionally used for its anti-inflammatory and antihistamine e=ects.

• Mechanism of Action: Stinging nettle is thought to act as a natural antihistamine. It may inhibit the production and release of histamines, thereby reducing symptoms associated with allergic reactions.
• Clinical Evidence: A study in The American Journal of Clinical Nutrition found that stinging nettle extract was e=ective in reducing symptoms of allergic rhinitis, which supports its use as a complementary treatment for seasonal allergies.

Bromelain

Bromelain is an enzyme derived from pineapple stems. It has anti-inflammatory and mucolytic properties.

• Mechanism of Action: Bromelain helps to reduce inflammation and break down mucus, which can alleviate nasal congestion and sinusitis commonly associated with seasonal allergies.
• Clinical Evidence: Research published in The Journal of Medicinal Food indicates that bromelain can reduce symptoms of sinusitis and improve overall nasal breathing, making it a useful addition to allergy management strategies.

N-Acetylcysteine (NAC)

NAC is a derivative of the amino acid cysteine and is known for its antioxidant and mucolytic properties.

• Mechanism of Action: NAC enhances the production of glutathione, a potent antioxidant that helps reduce oxidative stress. Additionally, NAC helps to thin mucus, making it easier to expel and thus relieving nasal congestion.
• Clinical Evidence: A study published in Lung suggests that NAC can reduce symptoms of chronic rhinosinusitis and improve mucus clearance, which can be beneficial for individuals su=ering from seasonal allergies.

Vitamin C

Vitamin C is a well-known antioxidant and immune system booster.

• Mechanism of Action: Vitamin C has anti-inflammatory e=ects and can reduce histamine levels in the body, which helps to mitigate allergic responses.
• Clinical Evidence: A review in Allergy and Asthma Proceedings highlights that Vitamin C can have a beneficial impact on allergy symptoms by reducing histamine release and supporting the immune system.

Conclusion

Incorporating Primal AR by Ready4.Health into a seasonal allergy relief regimen o=ers a multifaceted approach to managing symptoms. Each ingredient works through distinct mechanisms—ranging from stabilizing mast cells and reducing histamine release to improving mucus clearance and supporting overall immune function. By utilizing a combined approach, including lifestyle adjustments, one can manage and mitigate seasonal allergy symptoms e=ectively.

As with all supplements, it is essential to consult healthcare professionals before starting any new treatment, especially if you may have underlying health conditions or are taking other medications.

Primal AR – Ready4 Support

Directions: Loading dose: 2 capsules three times per day for 7-10 days.

Maintenance: 2 capsules per day or as recommended by your health care professional Does Not Contain: Gluten, yeast, artificial colors or flavors.

Cautions: If you are pregnant or nursing, consult with your health care practitioner before taking this product.

Serving Size: 2 Capsules Per

Container: 120 ct.

Primal AR+ Supplement Facts

*Daily Value not established

Other Ingredients: Hypromellose (Natural Vegetable Capsules) Magnesium Stearate, Silicon Dioxide and Stearic Acid

Consult with a doctor before taking any new supplements or nutraceuticals. This information and statements about Ready4. Health products have not been evaluated by the Food & Drug Administration. None of our products are intended to diagnose, treat, cure or prevent any disease. †These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:

• Nutritional and pharmacological importance of stinging nettle (Urtica dioica L): ncbi.nlm.nih.gov/pmc/articles/PMC9253158/
• Quercetin as a Therapeutic Product; Evaluation of its Pharmacological Action and Clinical Applications -PMCID: PMC10674654 -ncbi.nlm.nih.gov/pmc/articles/PMC10674654/
• Properties and Therapeutic Application of Bromelain: A Review: PMCID: PMC3529416 - ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
• Lung Publication; Advances in the Use of N-Acetylcysteine in Chronic Respiratory Diseases:ncbi.nlm.nih.gov/pmc/articles/PMC10526097/
• Allergy and Asthma Review: The eVects of vitamin C on respiratory, allergic and immunological diseases: www.ncbi.nlm.nih.gov/pmc/articles/PMC9970132/
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